Quinine Hydrochloride is primarily used as an antimalarial agent, treating and preventing malaria caused by Plasmodium parasites. It is also utilized for muscle relaxation, particularly in managing nocturnal leg cramps.

Quinine Sulphate treats malaria by attacking the parasite within red blood cells. It's mainly used for resistant strains of malaria. While it has been used for leg cramps, it's not typically recommended for that anymore. It's important to use quinine sulphate under medical supervision due to potential side effects.Quinine sulphate also used as base medicine for anti-aritmia. As per now is develop for pseudobulbar cure.