The cultivation of quinine plant in Indonesia especially in the island of Java is pioneered in year 1855 by Frans Wilhem Junghuhn, a German doctor and scientist on duty in the Netherlands.
At that time the Netherlands was motivated to gain advantage and benefit from quinine. The Netherlands really wanted to cultivated the quinine plant in their territory, Therefore they assigned Justus Karl Hasskarl, an ex Kebun Raya Bogor Director to obtain the quinine plant seeds from his native country, Bolivia.
A quantity of 121 boxes contain the seeds of Calisaya quinine plant was succeed to be brought under the escort of the Netherlands battle ships. But due to the long journey not all the seeds can be saved. From 70 seeds saved, hereinafter is given to Frans Wilhem Junghuhn as a close friend of Justus Karl Hasskarl which was on duty to cultivate the quinine plants. The seeds were later planted in Cibodas, Puncak (West Java). But, due to the inappropriate location, Junghuhn, later pick the west hillsides area of Malabar mountain in the area of Pangalengan, Southern Bandung.
The choice was proven to be very precise because the temperature and the rainfall in the area was very suitable for quinine plant. Ten years later in 1865 or one year after Junghuhn passed away, the quinine plant cultivation takes place on the large scale in the North Bandung Area. At that moment the government of The Netherlands brought in 500 gram @2800 seeds of ledegeriana quinine seeds which was obtain from Bolivia.